Thomas Streichert, Benjamin Otto, Claudia Schnabel, Gerhard Nordholt, Munif Haddad, Mario Maric, Astrid Petersmann, Roman Jung, and Christoph Wagener
BACKGROUND:Pneumatic tube systems (PTSs) for thetransport of blood samples are regaining popularityin medical centers after earlier reports that their usecould introduce preanalytical distortions such as hemolysis and changes in blood gases.
RESULTS:There were no significant differences intemperature, humidity, and pressure between themethods of transport, but we observed significantdifferences in 3-axis accelerations. The combined ef-fect of these forces could be described by the right-tailed area under the vector sum acceleration distri-bution. Our data show that this area correlated withPTS speed and that PTS speed and the area under thecurve exhibited a direct relation to the degree ofhemolysis.
CONCLUSIONS:Assessment of 3-axis acceleration byuse of data loggers can be used to identify preanalyti-cal deviations that result from the transportation ofblood samples in PTSs. Our approach could be usedfor the evaluation and regular control of PTSs with-out the need for repeated blood drawing and labora-tory analyses.
Olof Wallin, Johan Söderberg, Kjell Grankvist, P. Andreas Jonsson and Johan Hultdin. Department of Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden.
Background: Pneumatic tube transport of blood samples reduces turnaround times and labour. However, the preanalytical effects on new clinical chemistry parameters and instruments are not fully known. The aim of this study was to evaluate the effect of pneumatic tube transport on haematology and coagulation parameters, including platelet function with PFA-100®, and global coagulation with a thromboelastograph.
Results: No preanalytical effect of pneumatic tube transport could be seen for most haematology and coagulation parameters, as well as analysis with PFA-100®. For the thromboelastographic analysis, time to clot formation was shorter (–16%, p=0.037) in the transported samples. Treatment with acetylsalicylic acid had no effect on the majority of the test results.
Conclusions: Pneumatic tube transport does not introduce preanalytical errors when transporting samples for analysis of routine haematology, coagulation parameters and platelet function with the PFA-100®. We recommend manual transport of samples for analysis with thromboelastographic techniques.